Our immune system and the fight against disease

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Project Main Details

Our immune system and the fight against disease 
This is for an in-depth, but compelling, medical animation video to be used on company website and in investor presentations. Length will be approximately 2-3 minutes. We make our videos storydriven, interesting and engaging for our target audience. So even though this is scientific in nature (think Discovery Channel more than CSPAN), please try to do an audition demo that really connects with both the content and the prospective audience (investors, lay people, doctors) and tell the best story you can. Thanks for auditioning and providing a custom demo. 
2017-03-15 16:02:43 GMT
2017-03-24 13:00:00 (GMT -08:00) Pacific Time (US & Canada) 
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0 direct invitation(s) have been sent by the voice seeker resulting in 0 audition(s) and/or proposal(s) so far.
Voice123 SmartCast is seeking 50 auditions and/or proposals for this project (approx.) Invitations sent by SmartCast have resulted in 50 audition(s) and/or proposal(s) so far.

Project Parameters

The Voice Actor should be located in:
Flexible Price - USD 250 to USD 500
Training, business presentations, sales, and web sites
Via Internet: Wherever the internet goes
English - USA and Canada
Not defined
Middle Age Female OR Middle Age Male OR Senior Female OR Senior Male
• Audio files must be delivered via FTP/Dropbox/Google Drive/cloud
There are no special pre-, post-, or production requirements for this project.
Not defined
The voice seeker is willing to hire either union or non-union talents for this project

Script Details

Did you know that our immune system plays a critical role in identifying and destroying potentially harmful cells, such as cancer cells, every day? The immune system is made up of two parts that work together to defend the body. Innate immunity is a rapid but nonspecific response system and serves as the first line of defense against foreign invaders. Adaptive immunity is made up of highly specialized cells and molecules that specifically recognize and attack disease threats, such as cancer cells, bacteria and viruses. Unfortunately, cancer cells are often able to escape both the innate and adaptive immune responses, allowing them to survive, grow and spread throughout the body. Aduro, a leader in immune-based therapy, is developing cutting edge treatments that are designed to support the immune system to find, attack and kill cancer cells. Aduro’s first-in-class therapy, ADU-S100, is currently being tested and is designed to stimulate a person’s immune system to fight cancer through an immune pathway called STING. STING, or Stimulator of Interferon Genes, plays a critical role in amplifying both the innate and adaptive immune responses against tumors. Here’s how STING works. When STING is activated in cells within the tumor, this leads to stimulation of immune cells known as dendritic cells and cytotoxic T cells. These T cells are part of adaptive immunity and recognize specific markers on tumor cells and kill them. Unfortunately, the natural activation of STING is not always sufficient to prevent the growth and spread of cancer cells. ADU-S100 directly activates STING. Injection of ADU-S100 directly into tumors has shown a very strong anti-tumor immune response in pre-clinical studies. And, in these pre-clinical studies, because these anti-cancer immune cells circulate throughout the body, ADU-S100 has been shown to kill uninjected tumor cells that are located away from the injected tumor. This amplified immune response is targeted against a patient’s own unique tumor cells.
Aduro is working to develop technologies and treatments that amplify and modulate the body’s own immune system to fight cancer and other diseases. Now, ADU-S100’s targeted activation of the STING Pathway may provide a new exciting approach in the fight against cancer and other diseases.
Aduro Biotech… pioneering immunotherapy, transforming lives. 
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