CRISPR Video

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Project Main Details

CRISPR Video 
ZD1798320
This is a video that talks abouts Science and DNA. It will be avalaible on internet. Voice must be friendly but, try to not be so serious to make the information more affordable. Is possible that this can be the first video of many others so keep that in mind. Thanks! 
2017-01-05 16:56:00 GMT
2017-01-15 13:00:00 (GMT -04:00) Santiago 
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0 direct invitation(s) have been sent by the voice seeker resulting in 0 audition(s) and/or proposal(s) so far.
Voice123 SmartCast is seeking 35 auditions and/or proposals for this project (approx.) Invitations sent by SmartCast have resulted in 22 audition(s) and/or proposal(s) so far.

Project Parameters

The Voice Actor should be located in:
Fixed - USD 175
Training, business presentations, sales, and web sites
Via Internet: WEB
1 PAGES
English - USA and Canada
Not defined
Young Adult Male AND Middle Age Male
• Audio files must be delivered via email OR
• Audio files must be delivered via FTP/Dropbox/Google Drive/cloud
There are no special pre-, post-, or production requirements for this project.
Not defined
The voice seeker is willing to hire either union or non-union talents for this project

Script Details

Yes
N/A 
CRISPR Decoded

[CRISPR acronym defined via video animation]

It’s science’s POTENTIAL secret weapon for treating inherited diseases like , sickle cell anemia and muscular dystrophy.

To be specific — CRISPR uses a protein that cuts DNA. Basically, it edits your genes.

So, let’s say you want to fix some faulty DNA in a genome.

How does CRISPR work?

It’s a three-step process:

1) You tell CRISPR where the bad stuff is in the DNA.
2) CRISPR finds the bad stuff.
3) It starts cutting.

Wait… but how do you tell CRISPR where to cut?

You give it a guide molecule of RNA. These guide molecules are tiny (about 20 letters long, if you’re wondering), but that’s enough to point the CRISPR cutting protein to a specific location in the genome. Think of it like an itsy-bitsy tracking device.

Hold on — let’s go back. What happens after it finds the guide molecule?

We’ve got two options here:

Delete — Cut a gene with CRISPR, which can deactivate the bad gene.
Edit — CRISPR cuts, but now with a template for how to make a DNA repair. Here’s a suggestion, cell! After the repair, you’ve got a fresh, clean gene.

Hmmm. This seems pretty simple. Is CRISPR really such a big deal?

Yes, it most certainly is.

Consider sickle cell anemia. This disease causes crippling pain, organ failure, and premature death… all because of a single misspelled letter of DNA. Change that, and <poof>

Some scientists believe CRISPR could even be used to treat diseases like muscular dystrophy, and they’ve already cured mice this way.

OK, so getting the CRISPR ingredients into a human body isn’t going to be easy, but scientists are working on it. 
Please note that you should only use the script or your recording of it for auditioning purposes. The script is property, unless otherwise specified, of the voice seeker and it is protected by international copyright laws.

Voice-Seeker Details

81173
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2012-05-09
22

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