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Tone: Confident, street-smart, clear. Upbeat and optimistic, but slightly edgy. At times, even lighthearted. People remember humor. Make this complicated subject more accessible and conversational. 2016-02-24 23:18:31 GMT 2016-02-28 16:00:00 (GMT -07:00) Mountain Time (US & Canada) Yes (click here to learn more about ) Closed and fulfilled 32 32 0 direct invitation(s) have been sent by the voice seeker resulting in 0 audition(s) and/or proposal(s) so far. Voice123 SmartCast is seeking 40 auditions and/or proposals for this project (approx.) Invitations sent by SmartCast have resulted in 32 audition(s) and/or proposal(s) so far.
Hemophilia treatment has come a long way from on-demand to the current standard of care, prophylaxis.
To reduce the risk of bleeding, physicians often consider a prophylactic regimen for some of their patients in order to keep their Factor VIII levels above a certain minimum level.
However, the ultimate goal is helping all patients reach zero bleeds.
When factor VIII is infused, initially the entire dose enters the bloodstream, but is then used or removed by the body over time.
Typically, hemophilia A patients on prophylaxis infuse 2-4 times per week…
...without knowing how fast their FVIII levels are decreasing.
The study of what happens to medicines, such as Factor VIII, from when they enter the body until they leave is called Pharmacokinetics, or PK for short.
It comes from the Ancient Greek words that mean “drugs in motion.”
Let’s take a closer look at PK...
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