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are about to meet their match.
ALTABAX® (retapamulin ointment), 1% is the first and only impetigo treatment containing a pleuromutilin antibiotic that hits bacterial protein synthesis in three different ways.
Let’s take a closer look.
One line of attack stops normal 50S ribosomal formation – an action that results in an overall decrease in the cell’s ability to translate messenger RNA into proteins.
Another mode of action blocks P-site interactions with the transfer RNA that carries amino acids to the ribosome for incorporation into a protein. Since amino acids can't enter the site, protein synthesis cannot begin.
A third hit inhibits peptidyl transferase activity – the enzyme necessary for forming the bond between amino acids when a protein is being synthesized.
Altabax ointment’s three-pronged Mechanism of action has proven efficacy according to Phase 3 clinical studies.
Microbiological pathogens were eradicated in 91% of patients with no new pathogens present.
Patients with positive cultures for the two most common impetigo pathogens were also analyzed for treatment success.
Among patients who had MSSA at baseline, 92% achieved success.
For those who had Streptococcus pyogenes at baseline, 91% achieved success. And in clinical studies only 5.5% of patients experienced treatment-related adverse events.
ALTABAX® Ointment is a proven formulation that contains no additives...
Or added colors.
It consists of just two ingredients: the active ingredient retapamulin...
...and white petrolatum – nothing more. ALTABAX® Ointment is well tolerated by patients as young as nine months.
When fighting the pathogens of impetigo, hit hard with a one-two-three pronged mode of action found in ALTABAX® Ointment – the first and only one of its kind.
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