Voice over for a Novartis Pharma video

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Project Main Details

Voice over for a Novartis Pharma video 
This voice over record is for a series of videos for Novartis Pharmaceuticals.

Zometa (Zoh-meta)

zoledronic (zole-dron-ic)

myeloma (my-el-o-ma)

metastases (meh-tas-ta-sees)

2012-09-04 15:16:44 GMT
2012-09-04 22:00:00 (GMT -05:00) Eastern Time (US & Canada) 
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0 direct invitation(s) have been sent by the voice seeker resulting in 0 audition(s) and/or proposal(s) so far.
Voice123 SmartCast is seeking 50 auditions and/or proposals for this project (approx.) Invitations sent by SmartCast have resulted in 0 audition(s) and/or proposal(s) so far.

Project Parameters

The Voice Actor should be located in:
Student or Non-for-profit student project - USD 200
Training, business presentations, sales, and web sites
6 pages
English - USA and Canada
Middle Age Male
• Audio files must be delivered via email
There are no special pre-, post-, or production requirements for this project.
The Voice Actor should have at least 5 years of experience in the voice industry.
This is a non-union project

Script Details

***custom demo required*** 
Please see important safety information found in this video and the ************************************************************************************************

****** is indicated for the treatment of patients with multiple myeloma and documented bone metastases from solid tumors, in conjunction with standard antineoplastic therapy. Prostate cancer should have progressed after treatment with at least one hormonal therapy.

****** is contraindicated in patients with hypersensitivity to zoledronic acid or any components of ******* Hypersensitivity reactions, including rare cases of urticaria and angioedema, and very rare cases of anaphylactic reaction/ shock, have been reported. Patients being treated with ZOMETA should not be treated with Reclast® (zoledronic acid) as
they contain the same active ingredient.

In patients with impaired renal function, the risk of adverse reactions (especially renal adverse reactions) may be greater. ****** treatment is not recommended in patients with bone metastases with severe renal impairment. Preexisting renal insufficiency and multiple cycles of **************** bisphosphonates are risk factors for subsequent renal deterioration with ******* Do not use doses greater than 4 milligrams. ****** should be administered by IV infusion over no less than 15 minutes. Monitor serum creatinine before each dose.

Osteonecrosis of the jaw, or ONJ, has been reported predominantly in cancer patients treated with intravenous bisphosphonates, including ******* Many of these patients were also receiving chemotherapy and corticosteroids, which may be risk factors for ONJ. Postmarketing experience and the literature suggest a greater frequency of reports of ONJ based on tumor type (advanced breast cancer, multiple myeloma) and dental status (dental extraction, periodontal
disease, local trauma, including poorly fitting dentures). Many reports of ONJ involved patients with signs of local infection, including osteomyelitis. Cancer patients should maintain good oral hygiene and should have a dental examination with preventive dentistry prior to treatment with bisphosphonates. While on treatment, these patients should avoid invasive dental procedures, if possible, as recovery may be prolonged. For patients who develop ONJ while on bisphosphonate
therapy, dental surgery may exacerbate the condition. For patients requiring dental procedures, there are no data available to suggest whether discontinuation of bisphosphonate treatment reduces the risk of ONJ. A causal relationship between bisphosphonate use and ONJ has not been established. Clinical judgment of the treating physician should guide the management plan of each patient based on individual benefit/risk assessment.

**This is a portion of the script, full script to be provided later** 
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