Project Main Details
2010-05-18 16:35:07 GMT 2010-05-25 23:00:00 (GMT -07:00) Mountain Time (US & Canada) Yes (click here to learn more about ) Closed 0 0 0 direct invitation(s) have been sent by the voice seeker resulting in 0 audition(s) and/or proposal(s) so far. Voice123 SmartCast is seeking 20 auditions and/or proposals for this project (approx.) Invitations sent by SmartCast have resulted in 0 audition(s) and/or proposal(s) so far.
Ions travel down the flight tube at different velocities depending on their mass-to-charge ratio.
The arrival time of ions at the detector, which is correlated with their mass-to-charge ratio, is displayed as a mass spectrum, a plot of the ions’ mass-to-charge ratio and the number of ions detected.
For each sample, hundreds of individual mass spectra are collected and combined to generate a single averaged spectrum.
ProTS then estimates and subtracts background, estimates noise, and normalizes the averaged spectrum.
Using proprietary reference points, ProTS aligns the spectrum along the mass-to-charge axis.
The normalized and aligned spectrum can then be reliably compared with spectra from other individuals.
ProTS data analysis, supervised learning, and proprietary methodologies are used to compare spectra across clinically relevant populations and identify features which distinguish the groups. For example, Group A might represent patients who respond to a particular therapy; group B, those who do not.
The selected features are then incorporated into a novel classifier algorithm, a test which evaluates the spectra from multiple analyses of a patient sample and assigns that sample to one of the two predetermined groups.
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