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Project Main Details
Need a mature male voice for an educational DVD teaching about the brain. It is a small release of 500 units distributed free to schools. One section of the DVD features television spots with Garrick Utley so the client wants the other VO to be similar to his voice. There are also some technical words to be pronounced (e.g., Electroencephalogram). I have a pronunciation guide from the client, but you should be comfortable with speaking some scientific jargon. I had planed on using a studio on 14th and 6th Ave in Manhattan, but will be happy to discuss other options (e.g. if you are confident you can do it properly from a home studio).
Samples of your work can be emailed to me directly or as links. Looking to do this work early next week. The total script is 1200 words, generally read in a conversational tone. Sep 23, 2005 14:31:39 (GMT -05:00) Eastern Time (US & Canada) Sep 24, 2005 00:00:00 (GMT -05:00) Eastern Time (US & Canada) No (click here to learn more about
Project Parameters
• Phone Patch AND
• Audio files must be delivered via FTP
Script Details
http://www.awakepictures.com/garrick_utley_sample/utley.mp3
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Full Script for pricing reference:
Hello, I’m __________, for “Topics in Brain Science.”
Brain science is much more than a biological study. Its findings and the way we use them have the power to affect our future. It will influence us as individuals and as a society, not only in our health but also in how we regard and treat one another.
The brain is the organ of the mind, which makes us distinctively human. The brain gives rise to perception, reason, language, and social relations.
The brain is also subject to many of our still incurable or even untreatable diseases and disorders. But even here we find hope: brilliant researchers and brain doctors are working steadily toward healing conditions once though beyond help.
Listen to what David Alpay, a student who participated in a recent Brain Awareness Week event, said about his experiences:
“Brain science seeks to make sense of a world of unknowns. It lifts the veil that obscures our understanding of the mind. Brain science brings about rationality by seeking truth and a cure for disease. It endeavors to make sense not just of figures and data, but of the human experience.”
This young man put his finger exactly on what makes brain science so exciting and rewarding. It shines a bright and increasing light on the potential, the hope, the possibilities that lie within the human brain.
Using the tools of modern brain science, such as brain imaging, genetics, and rational drug development, brain scientists are bringing hope to those afflicted with a brain disease or disorder at any stage of life: early childhood, the mature years, and older age. Those same tools are explaining how we think and behave and bringing the possibility of helping people who are struggling with limitations that harm their quality of life or their relations with others.
This DVD, provided by the Dana Foundation to accompany the Dana Sourcebook of Brain Science, will highlight some of the major topics being studied by brain scientists.
What is the relationship between our genes and the brain? What are stem cells and what is their potential as therapeutic agents in brain disease? How do depression and stress affect our bodies? Can modern imaging techniques tell us about our brains: How do alcohol and drugs affect our brains? How might the arts benefit people with stroke or Alzheimer’s disease?
Some of these topics and ideas are controversial and students are encouraged to think about the material carefully and reach their own conclusions.
In addition to its work on behalf of brain research, the Dana Foundation offers the latest news and research developments in another compelling area: immunology. Dana supports research to learn how the body’s immune system protects us against infections and how it occasionally fails to function properly.
In education, the Dana Foundation has extended its long-time interest in the field to support innovative professional development of artists teaching the performing arts in public schools.
The Dana Foundation, the scientists of the Dana Alliance for Brain Initiatives, and the Dana Press are communicating the importance of brain research to the public. I hope you enjoy the overview of their efforts in this DVD, “Topics in Brain Science,” and that you take every opportunity to learn about the most extraordinary resource within us all—the human brain.
BRAIN IMAGING TIMELINE 1543: Artists in the painter Titian’s studio sketched detailed drawings of the brains of cadavers. This sketch appeared in a book by Dutch anatomist Andreas Vesalius, [Veh SAL Eus] which revolutionized the study of anatomy.
1861: French surgeon Paul Broca identified the speech center in the brain through autopsies.
1911: Santiago Ramon y Cajal’s [Ka HAL’s] drawings and staining methods advanced those of Camillo Golgi [GOAL JEE] for visualizing neurons, dendrites, and axons. Cajal promoted the “neuron theory,” the fundamental principle of modern neuroscience which holds that neurons are the basic unit of the central nervous system. More important, Cajal realized that neurons communicate across a small gap, or synapse.
1929: Electroencephalogram [EE lectro en cephalo gram] (EEG) introduced; measures and records minute wavelike electrical signals produced by neurons as they “fire.”
1973: First computed tomography (CT) camera; produces a composite image of the brain with a scanner that revolves around the skull, taking thousands of x-rays.
1975: First positron emission tomography [ta mog raphy] (PET) camera; uses the principle that blood is rushed to busy areas of the brain to deliver oxygen and nutrients to the neurons. Patients are injected with radioactive glucose, then scanned for the rays emitted as the solution metabolizes [meh tab OH LIZ es], highlighting neuronal activity.
1911: Santiago Ramon y Cajal’s drawings and staining methods advanced those of Camillo Golgi for visualizing neurons, dendrites, and axons. Cajal promoted the “neuron theory,” the fundamental principle of modern neuroscience which holds that neurons are the basic unit of the central nervous system. More important, Cajal realized that neurons communicate across a small gap, or synapse [sin apse].
1977: First magnetic resonance imaging (MRI) camera; produces images by subjecting the patient’s head to a strong magnetic field, followed by several pulses of radio waves, producing three-dimensional computer- generated images.
1992: Functional magnetic resonance imaging (fMRI) introduced; used to map brain activity by detecting variations in the response of hydrogen atoms when oxygen is present in the blood.
Genes and the Brain
A human cell
Each of the 100 trillion cells in the human body (except mature red blood cells) contains a copy of the entire human genome—all the genetic information necessary to build a human being. The cell nucleus is a separate compartment in the cell that contains six feet of DNA packed into 23 pairs of chromosomes [CHRO mah SOMES] We each inherit one set of 23 chromosomes from our mother and another set from our father. Egg and sperm cells carry single sets of 23 chromosomes.
DNA
The material from which the 46 chromosomes in each cell’s nucleus are formed is called DNA (deoxyribonucleic [DE ox E RI BO NU CLAY ic] acid). DNA contains the codes for the body’s approximately 30,000 genes, governing all aspects of cell growth and inheritance. DNA has a double-helix structure— two intertwined strands resembling a spiraling ladder. DNA consists of just a few kinds of atoms: carbon, hydrogen, oxygen, nitrogen, and phosphorus [Phos phor us]. Combinations of these atoms form the sugarphosphate backbone of the DNA—the sides of the ladder.
A chromosome
In the nucleus of any normal human cell there are 23 sets of chromosomes. Within each of the 46 chromosomes is bundled a double-stranded helix [Heel ix] of DNA. Each of the human chromosomes contains genes, the major functional units of DNA.
A gene
Each gene is a segment of DNA, typically several thousand base pairs long. Genes are copied into a molecule of RNA (ribonucleic [RI BOW NU CLAY ic] acid), which is translated to make a specific molecule, usually an amino[Ah MI NO] acid. Combinations of the atoms carbon, hydrogen, oxygen, nitrogen, and phosphorus form the four chemical bases in DNA: adenine [ADDenINE] (A), thymine (T), guanine [GwaNine](G), and cytosine [SytoSeen] (C). The bases form interlocking pairs that can fit together in only one way: A pairs with T; G pairs with C. Each such pair is called a base pair of DNA.
A protein
Proteins, which are made up of amino[Ah MEE NO] acids, are the body’s workhorses, essential components of all organs and chemical activities. Their function depends on their shapes, which are determined by the roughly 30,000 genes in the cell nucleus. Script
Hello, I’m __________, for “Topics in Brain Science.”
Brain science is much more than a biological study. Its findings and the way we use them have the power to affect our future. It will influence us as individuals and as a society, not only in our health but also in how we regard and treat one another.
The brain is the organ of the mind, which makes us distinctively human. The brain gives rise to perception, reason, language, and social relations.
The brain is also subject to many of our still incurable or even untreatable diseases and disorders. But even here we find hope: brilliant researchers and brain doctors are working steadily toward healing conditions once though beyond help.
Listen to what David Alpay, a student who participated in a recent Brain Awareness Week event, said about his experiences:
“Brain science seeks to make sense of a world of unknowns. It lifts the veil that obscures our understanding of the mind. Brain science brings about rationality by seeking truth and a cure for disease. It endeavors to make sense not just of figures and data, but of the human experience.”
This young man put his finger exactly on what makes brain science so exciting and rewarding. It shines a bright and increasing light on the potential, the hope, the possibilities that lie within the human brain............
............
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